Author

Yipin Lei

Silexon AI Technology (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Dan Yang ZhaoiD· 2 shared Fang WaniD· 2 shared Jianyang ZengiD· 2 shared Shuya LiiD· 2 shared Tingzhong TianiD· 2 shared Chengliang Hu· 1 shared Chunhao YangiD· 1 shared Enming YuaniD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Dan Yang ZhaoORCID

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2 papers

Recent·Most cited

A data-driven drug repositioning framework discovered a potential therapeutic agent targeting COVID-19

Yiyue Ge, Tingzhong Tian, Suling Huang, Fang Wan, Jingxin Li, Shuya Li, Xiaoting Wang, Hui Mei Yang, Lixiang Hong, Nian Wu, Enming Yuan, Yunan Luo, Lili Cheng, Chengliang Hu, Yipin Lei, , Jianyang Zeng

This paper presents a data-driven drug repositioning framework that identifies CVL218, a PARP1 inhibitor, as a potential therapeutic for COVID-19 through in silico and experimental validation.

Signal Transduction and Targeted Therapy · Apr 24, 2021Peer-reviewedSystems Biology

CAMP: a Convolutional Attention-based Neural Network for Multifaceted Peptide-protein Interaction Prediction

Yipin Lei, Shuya Li, Ziyi Liu, Fang Wan, Tingzhong Tian, Shao Li, Dan Yang Zhao, Jianyang Zeng

CAMP predicts peptide-protein interactions and binding residues using a convolutional attention-based neural network, outperforming existing methods on benchmark datasets.

bioRxiv · Nov 16, 2020 · PreprintBioinformatics