Pavlovian conditioned approach with different reward magnitudes reveals opposing effects of acute and chronic semaglutide treatment
Stephanie S. Desrochers, Raymond Li, Shelly B. Flagel
This study compares acute and chronic semaglutide effects on conditioned approach behavior in rats, finding chronic treatment increases sign-tracking while acute treatment decreases it, suggesting different impacts on reward-motivated behavior.
bioRxiv · Sep 14, 2026 · PreprintNeuroscience