Author

Santosh Manicka

Tufts UniversityORCID 0000-0002-8747-2363Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Santosh Manicka1 paper · Allen Discovery Center at Tufts University;

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

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Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Michael G. LeviniD· 2 shared David MurrugarraiD· 1 shared Kathleen JohnsoniD· 1 shared Vaibhav P. PaiiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersDevelopmental Biology

Michael G. LevinORCID

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2 papers

Recent·Most cited

Information integration during bioelectric regulation of morphogenesis in the embryonic frog brain

Santosh Manicka, Vaibhav P. Pai, Michael G. Levin

The paper develops a bioelectric-genetic dynamical model to understand how spatial voltage patterns influence gene expression and brain development in Xenopus embryos, revealing mechanisms of information integration and plasticity.

iScience · Nov 4, 2023Peer-reviewedDevelopmental Biology

The nonlinearity of regulation in biological networks

Santosh Manicka, Kathleen Johnson, Michael G. Levin, David Murrugarra

The paper analyzes regulatory nonlinearity in biological networks using Boolean models and finds that biological regulation is generally less nonlinear than expected, with cancer networks showing higher and more variable nonlinearity.

npj Systems Biology and Applications · Apr 4, 2023Peer-reviewedSystems Biology