Author

Jana Zecha

AstraZeneca (United States)ORCID 0000-0002-8767-6294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Anna Asplund· 1 shared Arthur Eng Lip YeowiD· 1 shared Arunasingam AbayasingamiD· 1 shared Basak EraslaniD· 1 shared Bernhard KüsteriD· 1 shared Björn M. Hallström· 1 shared Branka Grubor‐BaukiD· 1 shared Chen MengiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Anna Asplund

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2 papers

Recent·Most cited

A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S) after the first, second and third doses

Feargal J. Ryan, Todd S. Norton, Conor McCafferty, Stephen J. Blake, Natalie E. Stevens, Jane James, Georgina L. Eden, Yee C. Tee, Saoirse C. Benson, Makutiro Ghislain Masavuli, Arthur Eng Lip Yeow, Arunasingam Abayasingam, David Agapiou, Hannah Stevens, Jana Zecha, , David John Lynn

This study compares innate and adaptive immune responses to two COVID-19 vaccines in adults after multiple doses, identifying differences linked to antibody, T cell responses, and reactogenicity.

medRxiv · Sep 22, 2022 · PreprintGenetic & Genomic Medicine

A deep proteome and transcriptome abundance atlas of 29 healthy human tissues

Dongxue Wang, Basak Eraslan, Thomas Wieland, Björn M. Hallström, Thomas A. Hopf, Daniel Paul Zolg, Jana Zecha, Anna Asplund, Li-hua Li, Chen Meng, Martin Frejno, Tobias Schmidt, Karsten Schnatbaum, Mathias Wilhelm, Fredrik Pontén, , Bernhard Küster

The paper creates a proteome and transcriptome atlas of 29 human tissues, revealing differences in mRNA-protein abundance and challenges in proteogenomics.

Molecular Systems Biology · Feb 1, 2019Peer-reviewedSystems Biology