Automated Cell Type Annotation with Reference Cluster Mapping
Valerio Galanti, Lingting Shi, Elham Azizi, Yining Liu, Andrew J. Blumberg
This paper introduces RefCM, a method that improves cell type annotation in scRNA-seq data using optimal transport and integer programming, achieving accurate cross-technology, cross-tissue, and cross-species mappings.
bioRxiv · Nov 30, 2024 · PreprintBioinformatics