Author

Ana Rita Fernandes

University of CoimbraORCID 0000-0002-8787-7854Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Ana Rita Fernandes1 paper · Centro de Neurociências e Biologia Celular

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Ana Carolina da SilvaiD· 2 shared Carina HenriquesiD· 2 shared Diana Duarte LoboiD· 2 shared Luís Pereira de AlmeidaiD· 2 shared Miguel Monteiro LopesiD· 2 shared Rui Jorge NobreiD· 2 shared Amal Dakka· 1 shared Anu Bhattacharyya· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersMolecular Biology

Ana Carolina da SilvaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 2, 2025

rAAV-Delivered Bicistronic Artificial microRNAs for Allele-Specific Silencing Improve Motor and Molecular Outcomes in Spinocerebellar Ataxia Type 3

Ana Carolina da Silva, Carina Henriques, Diana Duarte Lobo…·Luís Pereira de Almeida

This paper develops and tests rAAV-delivered bicistronic artificial microRNAs to selectively silence mutant ATXN3 in SCA3 mouse models, showing improved motor function and reduced mutant protein aggregates.

DOI 10.1101/2025.10.02.680011

mouseexperimental assay

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Molecular BiologybioRxivPreprintOct 2, 2025

AAV-mediated allele-specific silencing alleviates neuropathology in a novel non-human primate model of Spinocerebellar ataxia type 3

Carina Henriques, Diana Duarte Lobo, Ana Carolina da Silva…·Rui Jorge Nobre

This study evaluates AAV9-miR-ATXN3 in a non-human primate model of SCA3, showing reduced neuropathology through allele-specific silencing of mutant ATXN3.

DOI 10.1101/2025.10.02.680027

non-human primateexperimental assay

𝕏 PostBluesky