Beta-hairpin Mechanism of Autoinhibition and Activation in the Kinesin-2 Family
Stephanie Webb, Katerina Toropova, Aakash Gautam Mukhopadhyay, Stephanie D. Nofal, Anthony J. Roberts
The paper identifies a beta-hairpin motif in kinesin-2 that regulates motility by sequestering motor domains, revealing its role in activation and coordination with dynein.
Nature Structural & Molecular Biology · Jul 29, 2025Peer-reviewedCell Biology