Application of single nuclei RNA sequencing to assess the hepatic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin
Rance Nault, Kelly Alana Fader, Sudin Bhattacharya, Tim R. Zacharewski
This study uses single nuclei RNA sequencing to identify cell-specific transcriptional changes and population shifts in mouse liver exposed to TCDD, revealing increased macrophages and RAS signaling in nonparenchymal cells.
Cellular and Molecular Gastroenterology and Hepatology · Aug 10, 2020Peer-reviewedMolecular Biology