Multi-omics Differential Inference for Functional Interpretation (MoDIFI): A Statistical Framework to Prioritize Cell Lines for Neurodevelopmental Variants
Arvinden VR, Grace Tzun-Wen Shaw, Juana G. Manuel, Timothy L. Mosbruger, Hillary B. Heins, Jeffrey K. Ng, H. Kim, Tristan J. Hayeck, Tychele N. Turner
The paper develops MoDIFI, a Bayesian framework to prioritize cell lines and regulatory regions for testing noncoding variants associated with neurodevelopmental disorders.
bioRxiv · Jan 29, 2026 · PreprintGenomics