Author

Joseph McTiernan

University of California, MercedORCID 0000-0002-8827-035XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Ajay GopinathaniD· 2 shared Michael E. ColviniD· 2 shared Roya ZandiiD· 2 shared Siyu LiiD· 1 shared Thomas E. KuhlmaniD· 1 shared U. MohideeniD· 1 shared Yuanzhong ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

Ajay GopinathanORCID

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2 papers

Recent·Most cited

SARS-CoV-2 membrane protein conformations induce distinct membrane curvatures

Joseph McTiernan, Roya Zandi, Michael E. Colvin, Ajay Gopinathan

This study shows SARS-CoV-2 M protein conformations induce distinct membrane curvatures, matching virion regions and enabling spatial segregation through curvature-mediated interactions.

bioRxiv · Jul 8, 2026 · PreprintBiophysics

Clustering of SARS-CoV-2 membrane proteins in lipid bilayer membranes

Joseph McTiernan, Yuanzhong Zhang, Siyu Li, Thomas E. Kuhlman, U. Mohideen, Michael E. Colvin, Roya Zandi, Ajay Gopinathan

This study shows that M protein interactions alone can drive clustering in ERGIC-like lipid bilayers, with direct interactions being stronger than membrane-mediated ones.

PLoS Computational Biology · Apr 27, 2026Peer-reviewedBiophysics