Katherine A Aracena

The paper introduces EpiVar Browser, a tool for exploring epigenomics data under controlled access, enabling genotype-chromatin phenotype analysis without releasing identifiable information.

The paper uses mSTARR-seq to show DNA methylation interacts with environmental factors like IFNA and influenza virus in human macrophages, but not for early life adversity sites.

The paper uses genome graphs to detect polymorphic mobile elements in active epigenomic states during influenza infection, revealing novel peaks and modifying quantitative trait loci estimates.

The paper shows ancestry-related differences in transcriptional response to influenza are driven by epigenetic variation and genetic control of enhancer activity.

The paper identifies transposable elements as the main source of novelty in primate gene regulation by analyzing conserved and newly evolved cis-regulatory elements across six primate species.