Author

Hugo D. Williams

University of BirminghamORCID 0000-0002-8833-7913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:DNA methylation· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1

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Michael J. HannoniD· 1 shared Samuel J. DettmeriD· 1 shared Sumit BajpaiiD· 1 shared

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1 shared paperBiophysics

Michael J. HannonORCID

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1 paper

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BiophysicsJournal of the American Chemical SocietyPeer-reviewedOct 22, 2025

A Flexible Quadruple-Stranded Helicate Demonstrates a Strong Binding Preference for DNA Three-Way Junctions by Induced-Fit

Hugo D. Williams, Samuel J. Dettmer, Sumit Bajpai, Michael J. Hannon

This paper describes a quadruple-stranded helicate that preferentially binds DNA three-way junctions over four-way junctions, revealing the importance of size and shape in junction recognition.

4 citations

DNA methylationmechanistic / dynamical model