A unified framework for cell-type-specific eQTLs prioritization by integrating bulk and scRNA-seq data
Xinyi Yu, Xianghong Hu, Xiaomeng Wan, Zhiyong Zhang, Xiang Wan, Mingxuan Cai, Tianwei Yu, Jiashun Xiao
This paper introduces IBSEP, a statistical framework that integrates bulk and scRNA-seq data to prioritize cell-type-specific eQTLs, showing improved performance over existing methods.
The American Journal of Human Genetics · Jan 16, 2025Peer-reviewedGenetic & Genomic Medicine