Author

Timothy Chappell

Queensland University of TechnologyORCID 0000-0002-8862-7048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:machine learning (classical)· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

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Dimitri PerriniD· 1 shared Jacob BradfordiD· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperBioinformatics

Dimitri PerrinORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintFeb 14, 2020

Faster and better CRISPR guide RNA design with the Crackling method

Jacob Bradford, Timothy Chappell, Dimitri Perrin

Crackling improves CRISPR guide RNA design by combining scoring methods and using ISSL for faster off-target scoring, outperforming existing tools on 12 genomes.

DOI 10.1101/2020.02.14.950261

CRISPR screenstatistical model

𝕏 PostBluesky