Quantification of DNA methylation using methylation-sensitive restriction enzymes and multiplex digital PCR
Rogier J. Nell, Debby van Steenderen, Nino V. Menger, Thomas J. Weitering, Mieke Versluis, Pieter A. van der Velden
This study introduces a digital PCR method for accurate DNA methylation quantification without bisulphite treatment, validated using RASSF1A promoter methylation in healthy and cancer samples.
Human Mutation · Sep 19, 2020Peer-reviewedGenomics