Author

Charalampos P. Triantafyllidis

University of OxfordORCID 0000-0002-8890-6936Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:graph neural network· 1

Frequent Co-Authors

Francesca Meteora BuffaiD· 2 shared Linda van BijsterveldtiD· 2 shared Adrian Llewellyn HarrisiD· 1 shared Alan McIntyreiD· 1 shared Alessandro BarberisiD· 1 shared Ana MiariD· 1 shared Andrew DhawaniD· 1 shared Enio GjergaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Francesca Meteora BuffaORCID

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3 papers

Recent·Most cited

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedAug 12, 2025

Causality-aware graph neural networks for functional stratification and phenotype prediction at scale

Charalampos P. Triantafyllidis, Ricardo J. Aguas

The paper develops causality-aware graph neural networks to classify gene regulatory networks and predict phenotypes across cancer types and TP53 mutation states.

2 citations

humanbulk RNA-seq

Cancer BiologybioRxivPreprintJun 23, 2022

Reconstructing the functional effect of TP53 somatic mutations on its regulon using causal signalling network modelling

Charalampos P. Triantafyllidis, Alessandro Barberis, Ana Miar…·Francesca Meteora Buffa

The paper uses network modeling to analyze how TP53 mutations affect gene regulation across cancer types and samples.

DOI 10.1101/2022.06.23.497293

humanbulk RNA-seq

GenomicsbioRxivPreprintAug 30, 2021

Dicer-to-Argonaute switch controls biogenesis of oncogenic miRNA

Laura M. Winchester, Linda van Bijsterveldt, Andrew Dhawan…·Francesca Meteora Buffa

The paper identifies a switch from DICER-dependent to Argonaute-mediated miRNA biogenesis in cancer, showing that non-canonical processing of oncogenic miRNAs promotes cancer progression.

1 citation

humanbulk RNA-seq