Transgenic mice overexpressing mutant TDP-43 show aberrant splicing of autism associated gene Zmynd11 prior to onset of motor symptoms
Ramesh K. Narayanan, Ajay Panwar, Tim J. Butler, Anthony N. Cutrupi, Marina L. Kennerson, Steve Vucic, Balasubramaniem Ashokkumar, Marie Mangelsdorf, Robyn H. Wallace
This study shows that mutant TDP-43 causes aberrant splicing of Zmynd11 in mice before motor symptoms appear.
bioRxiv · Dec 11, 2022 · PreprintNeuroscience