Hematological and genetic basis of clinical heterogeneity of HemoglobinE/β-thalassemia
Farjana Akther Noor, Mohabbat Hossain, Suprovath Kumar Sarker, Khalid Arafath, Subarna Sayed Ety, Jeba Atkia Maisha, Mohammad Al Mahmud‐Un‐Nabi, Nusrat Sultana, Golam Sarower Bhuyan, A. K. M. Ekramul Hossain, Waqar Ahmed Khan, Hossain Uddin Shekhar, Firdausi Qadri, Kaiissar Mannoor
The paper investigates the hematological and genetic factors contributing to clinical variability in HbE/β-thalassemia patients, identifying HbF and HbE levels and specific SNPs as modifiers of disease severity.
bioRxiv · Feb 23, 2026 · PreprintGenetics