Kaiissar Mannoor

Hemodynamic-Structural Multi-Fidelity Assessment of Endovascular Flow Diversion Strategies for Cerebral Aneurysm Treatment: An Integrated Computational and Experimental Framework

The paper evaluates hemodynamic and structural outcomes of endovascular flow diversion strategies for cerebral aneurysms using computational models and experimental tests.

Structure-Based and Stability-Validated Prioritization of BACE1 Inhibitors Integrating Meta-Ensemble QSAR and Molecular Dynamics

This study develops a computational framework integrating QSAR, molecular docking, and ADMET profiling to prioritize BACE1 inhibitors, identifying seven leads with stable binding and favorable properties.

Hematological and genetic basis of clinical heterogeneity of HemoglobinE/β-thalassemia

The paper investigates the hematological and genetic factors contributing to clinical variability in HbE/β-thalassemia patients, identifying HbF and HbE levels and specific SNPs as modifiers of disease severity.

Molecular Investigation of TSHR gene in Bangladeshi Congenital Hypothyroid patients

The paper identifies two TSHR gene mutations in congenital hypothyroid patients and evaluates their impact on drug binding and protein stability using computational methods.