RIPK3-RNASE1 axis as a potential therapeutic and clinical monitoring target in VEXAS syndrome
Kana Higashitani, Tatsuma Ban, Yohei Kirino, Go R Sato, Soichiro Adachi, Yuki Iizuka, Ayaka Maeda, Osamu Ohara, Hideaki Nakajima, Tomohiko Tamura
This study identifies the RIPK3-RNASE1 axis as a potential biomarker and therapeutic target in VEXAS syndrome by linking genetic mutations to disease activity and pathological features.
bioRxiv · Feb 6, 2026 · PreprintImmunology