Author

Mark N. Brook

Institute of Cancer ResearchORCID 0000-0002-8969-2378Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alison M. DunningiD· 1 shared Amber WilcoxiD· 1 shared André Lopes CarvalhoiD· 1 shared Andrew BerchuckiD· 1 shared Andrew Tan ChaniD· 1 shared Angela CoxiD· 1 shared Angeline S. AndrewiD· 1 shared Anna DeFazioiD· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Alison M. DunningORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS ONEPeer-reviewedFeb 5, 2020

iCARE: An R Package to Build, Validate and Apply Absolute Risk Models

Parichoy Pal Choudhury, Paige Maas, Amber Wilcox…·Nilanjan Chatterjee

iCARE is an R package for building, validating, and applying absolute risk models using user-defined inputs and SNP data, demonstrated with breast cancer.

100 citationstop 1%

statistical modelsoftware / tool

GenomicsNature CommunicationsPeer-reviewedJan 25, 2019

Shared heritability and functional enrichment across six solid cancers

Xia Jiang, Hilary K. Finucane, Fredrick R. Schumacher…·Patricia A. Ganz

This study quantifies genetic correlations between six solid cancers and other diseases using GWAS data, finding shared heritability and functional enrichment in regulatory regions.

110 citationstop 1%

humanGWAS summary statistics