Calmodulin binding is required for calcium mediated TRPA1 desensitization
Justin H. Sanders, Camila Garcia, Kehinde M. Taiwo, Gregory Quevedo, Glory A. Adekanye, Avnika P. Bali, Candice E. Paulsen
This study identifies a CaM binding element in TRPA1 that is essential for Ca2+-mediated desensitization and reveals a mechanism by which CaM regulates TRPA1 function.
Nature Communications · Sep 30, 2025Peer-reviewedBiochemistry