An open imaging and AI resource enabling unbiased quantification of extrachromosomal DNA at scale
Poorya Behnamie, River Summers, Jingting Chen, Aarav Mehta, Adesuwa Igbinigie, Qin Liu, Molly Murray, Damien Guilbaud, Marc Niethammer, Elizabeth Brunk
The paper provides an open resource for automated ecDNA quantification, comparing methods and introducing ecCount to reduce count bias.
bioRxiv · Sep 24, 2026 · PreprintGenetics