Computational Translation of Mouse Models of Osteoarthritis Predicts Human Disease
M. Frost, Brendan K. Ball, Meghana Pendyala, Stephen R. Douglas, Douglas K. Brubaker, Deva D. Chan
The paper evaluates the translatability of two mouse osteoarthritis models to human transcriptomics data using TransComp-R, finding that ACLR better predicts human OA conditions.
Osteoarthritis and Cartilage · Sep 23, 2025Peer-reviewedSystems Biology