Deva D. Chan

This study compares HA and HAS enzyme expression in kidney development, health, disease, and recovery, identifying distinct roles of HAS1 and HAS2 in fibroblast activation linked to fibrosis progression versus resolution.

This study analyzes gait parameters in mice from 6 to 16 weeks of age, identifying age- and sex-based differences in gait maturation and functional groupings.

The paper identifies conserved molecular pathways in spaceflight-induced sarcopenia using cross-species analysis and develops a model linking transcriptional changes to locomotion deficits.

The paper evaluates the translatability of two mouse osteoarthritis models to human transcriptomics data using TransComp-R, finding that ACLR better predicts human OA conditions.

The paper examines how antibiotic-induced changes in gut microbiota correlate with serum cytokine levels in mice, identifying specific microbial-taxa-cytokine relationships.

This study shows ROS inhibit myosin phosphorylation to counteract wound contraction, delay closure, and impair regrowth, while chronic ROS depletion alters tissue stiffness and impairs healing.

This study examines correlations between joint biomechanics and tissue-specific properties in ovine stifles to understand knee health indicators.

This study creates composite agarose-collagen hydrogels to support chondrocyte culture and mechanotransduction, showing improved mechanical properties and glycosaminoglycan production over 21 days.