Madushani Herath

Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal-Glial Synapses and Reduced Expression in Nlgn3R451C Mice

This study quantifies Nlgn3 mRNA expression in the enteric nervous system and shows the R451C mutation reduces it in specific neuronal subpopulations.

The autism-associated Neuroligin-3 R451C mutation alters mucus density and the spatial distribution of bacteria in the mouse gastrointestinal tract

This study shows that the Neuroligin-3 R451C mutation in mice increases mucus density and alters bacterial distribution near the ileum, potentially contributing to microbial dysbiosis in ASD.

Caecal dysfunction in the NL3R451C mouse model of autism

This study investigates caecal dysfunction in NL3R451C mice, a model of autism, finding altered motility patterns and reduced secretion in response to a nicotinic agonist.