MicroRNA-148a Regulates Low-Density Lipoprotein Metabolism by Repressing the (Pro)renin Receptor
Na Wang, Lishu He, Hui Lin, Lunbo Tan, Yuan Sun, Xiaoying Zhang, A.H. Jan Danser, Hong S. Lu, Yongcheng He, Xifeng Lu
This study shows miR-148a regulates LDL metabolism by suppressing (P)RR expression, which in turn reduces LDLR abundance and cellular LDL uptake.
PLoS ONE · May 21, 2020Peer-reviewedMolecular Biology