Author

Jian Guo

Zhejiang UniversityORCID 0000-0002-9007-4307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:dimensionality reduction· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:imaging· 1 Research Focus:imputation· 1 Organism:multiple species· 1

Frequent Co-Authors

Bo HaniD· 2 shared Gaoliang Deng· 2 shared Mengze DuiD· 2 shared Chen Rui· 1 shared Feng LiuiD· 1 shared Fusong WangiD· 1 shared Guowei ZhangiD· 1 shared Jiankang Han· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Bo HanORCID

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2 papers

Recent·Most cited

A foundation AI model enhances electron microscopy image analysis

Mengze Du, Yuwei Wang, Lijun Xie, Gaoliang Deng, Jian Guo, Bo Han, Zhong‐Hua Chen, Chen Rui, Jiankang Han, Yuan Chen, Yanru Zhao, Runzhou Cao, Fusong Wang, Kun Li, Yu Wang, , Xia Feng

DF5T improves EM image quality through five tasks, enhancing segmentation and 3D restoration of organelles.

bioRxiv · Mar 3, 2026 · PreprintCell Biology

EMCF ecosystem: Towards pretrained foundation model for electron microscopy image analysis

Zeyu Yu, Jian Guo, Feng Liu, Mengze Du, Shan Zhen Xu, Guowei Zhang, Li Xie, Bo Han, Zhonghua Chen, Gaoliang Deng, Rui Chen, Yong Ming He, Xuping Feng

The paper introduces EMCFsys, an ecosystem for electron microscopy image analysis, improving image restoration and analysis efficiency with a benchmark dataset, foundation model, and restoration model.

bioRxiv · Dec 11, 2025 · PreprintCell Biology