Author

Zachary Ardern

Technical University of MunichORCID 0000-0002-9008-0897Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:E. coli· 2 Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Alina Glaub· 1 shared Anne‐Kristin KasteriD· 1 shared Christopher HuptasiD· 1 shared Habibu AliyuiD· 1 shared Klaus NeuhausiD· 1 shared Sagarika Chakraborty· 1 shared Siegfried SchereriD· 1 shared Stefan WichmanniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 7 mutual co-author links

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1 shared paperMolecular Biology

Alina Glaub

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3 papers

Recent·Most cited

Annotating Hypothetical Proteins in Escherichia coli K-12

Sagarika Chakraborty, Zachary Ardern, Habibu Aliyu, Anne‐Kristin Kaster

This study uses machine learning and experimental validation to annotate hypothetical proteins in E. coli K-12, demonstrating the power of combining omics data with AI.

Computational and Structural Biotechnology Journal · Jan 1, 2025Peer-reviewedBioinformatics

Computational design of genes encoding completely overlapping protein domains: Influence of genetic code and taxonomic rank

Stefan Wichmann, Siegfried Scherer, Zachary Ardern

The paper designs artificial overlapping genes and finds that virus genes are less suitable for OLGs than bacterial or eukaryotic genes, with genetic code structure influencing design success.

bioRxiv · Sep 25, 2020 · PreprintBioinformatics

Improving Bacterial Ribosome Profiling Data Quality

Alina Glaub, Christopher Huptas, Klaus Neuhaus, Zachary Ardern

The paper analyzes ribosome profiling data from E. coli to identify optimal parameters for improving data quality and gene annotation.

bioRxiv · Dec 3, 2019 · PreprintMolecular Biology