Per-residue optimisation of protein structures: Rapid alternative to optimisation with constrained alpha carbons
Ondřej Schindler, Gabriela Bučeková, Tomáš Svoboda, Radka Svobodová Vařeková
This paper introduces a method to optimise protein structures more efficiently than traditional methods, achieving results comparable to constrained alpha carbon optimisation in less time.
bioRxiv · Nov 24, 2025 · PreprintBioinformatics