Knockdown of PHOX2B in the retrotrapezoid nucleus reduces the central CO2 chemoreflex in rats
Silvia Cardani, Tara Adele Janes, William Betzner, Silvia Pagliardini
This study shows that reducing PHOX2B in the retrotrapezoid nucleus of rats impairs CO2 chemoreflex during hypercapnia without affecting breathing in room air or hypoxia.
eLife · Feb 14, 2024Peer-reviewedNeuroscience