Author

Alexandre Mahrach

Centre National de la Recherche ScientifiqueORCID 0000-0002-9077-5808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:simulation· 1

Frequent Co-Authors

Albert CompteiD· 1 shared Carl van Vreeswijk· 1 shared Christos ConstantinidisiD· 1 shared David Bestue· 1 shared David HanseliD· 1 shared Guang CheniD· 1 shared Nuo LiiD· 1 shared Xue-Lian QiiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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1 shared paperNeuroscience

Albert CompteORCID

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2 papers

Recent·Most cited

Cholinergic neuromodulation of prefrontal attractor dynamics controls performance in spatial working memory

Alexandre Mahrach, David Bestue, Xue-Lian Qi, Christos Constantinidis, Albert Compte

The paper shows that cholinergic neuromodulation improves spatial working memory by altering prefrontal attractor dynamics through increased neural excitability and reduced correlations.

Journal of Neuroscience · Apr 19, 2024Peer-reviewedNeuroscience

Mechanisms underlying the response of mouse cortical networks to optogenetic manipulation

Alexandre Mahrach, Guang Chen, Nuo Li, Carl van Vreeswijk, David Hansel

The paper investigates how mouse cortical networks respond to optogenetic stimulation of PV neurons, finding paradoxical activity changes in layer 5 and proposing network architectures that explain these responses.

eLife · Jan 17, 2020Peer-reviewedNeuroscience