Self-organization in brain tumors: how cell morphology and cell density influence glioma pattern formation
Sara Jamous, Andrea Comba, Pedro Ricardo Lowenstein, Sébastien Motsch
The paper uses an agent-based model to show that glioma cell morphology and density influence self-organization patterns like flocks and streams, with higher density reducing flocks and increasing streams, linking these patterns to tumor malignancy.
PLoS Computational Biology · May 7, 2020Peer-reviewedSystems Biology