The ratio of adaptive to innate immune cells differs between genders and associates with improved prognosis and response to immunotherapy
Johanne Ahrenfeldt, Ditte Sigaard Christensen, Andreas B. Østergaard, Judit Kisistók, Mateo Sokač, Nicolai J. Birkbak
The paper defines an adaptive-to-innate immune ratio from bulk RNAseq data and shows it correlates with improved prognosis and immunotherapy response, with gender-specific differences.
PLoS ONE · Feb 6, 2023Peer-reviewedBioinformatics