Luiz Felipe Piochi

BindCORE improves prediction of interaction sites in intrinsically disordered regions by integrating biophysical ensemble features, outperforming sequence-based methods.

The paper introduces PROTEUS, a method to assess protein conformational plasticity using a generative model, showing it correlates with molecular dynamics data and identifies functionally plastic proteins.

ppIRIS predicts bacterial protein-protein interactions using deep learning, achieving high accuracy and enabling proteome-wide screening, with applications in identifying virulence pathways and host-pathogen interactions.