Genome-wide association analysis reveals insights into the molecular aetiology underlying dilated cardiomyopathy
Sean Lee Zheng, Albert Henry, Douglas Ewan Cannie, Michael Lee, David Miller, Kathryn A. McGurk, Isabelle Bond, Xiao Yun Xu, Hanane G. Issa, Catherine Francis, Antonio de Marvao, Pantazis I. Theotokis, Rachel J. Buchan, Doug Speed, Erik Abner, , Patrick T. Ellinor
This study identifies 80 genetic loci and 61 effector genes associated with dilated cardiomyopathy through GWAS and integrates transcriptomic data to uncover biological pathways and cellular states involved in the disease.
Nature Genetics · Nov 21, 2024Peer-reviewedGenetic & Genomic Medicine