Author

Wei Wang

Nanjing UniversityORCID 0000-0002-9176-5150Unclaimed ORCID profile · follow to get notified of new preprints

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Wei Wang59 papers · University of California San Diego

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Systems Biology· 1

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Organism:human· 1 Approach:statistical model· 1

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Chen Yu· 1 shared Xiao‐Peng ZhangiD· 1 shared

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2025-2025 · peak 1/yr

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Chen Yu

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Systems BiologybioRxivPreprintJul 20, 2025

Dysfunction of microglia-mediated synaptic pruning in Autism spectrum disorder

Chen Yu, Xiao‐Peng Zhang, Wei Wang

This study investigates how microglia-mediated synaptic pruning is disrupted in ASD by integrating inflammatory and synaptic signaling pathways, showing that reduced synaptic activity and pro-inflammatory activation lead to excessive synaptic accumulation.

DOI 10.1101/2025.07.20.665801

humanstatistical model

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