Anjan Bhattarai

Multimodal MRI Insights into Glymphatic Clearance and Blood-Brain Barrier Integrity in Healthy Aging

This study uses multimodal MRI to assess age-related changes in BBB permeability and glymphatic clearance in healthy adults, finding reduced Kw, increased FW, and decreased DTI-ALPS in older individuals.

Kinetic modeling of 18F-PI-2620 binding in the brain using an image-derived input function with total-body PET

This study uses a total-body PET scanner to quantify tau binding and tracer kinetics in the brain using an image-derived input function and explores scan duration effects.

Network diffusion model predicts neurodegeneration in limb-onset amyotrophic lateral sclerosis

This study uses a Network Diffusion Model to predict neurodegeneration patterns in limb-onset ALS by correlating simulated pathology spread with MRI-measured atrophy.

Serial assessment of iron in the motor cortex in limb-onset Amyotrophic Lateral Sclerosis using Quantitative Susceptibility Mapping

This study uses QSM to assess iron dysregulation in the motor cortex of limb-onset ALS patients over six months, finding increased QSM in lumbar-onset patients compared to controls and no significant change over time.