Andrea Álvarez-Pérez

Decoding cell-type-specific alterations in Alzheimer's disease through scRNA-seq and network analysis

This study uses scRNA-seq and network analysis to identify cell-type-specific transcriptional changes in Alzheimer's disease, revealing dysregulation in neurons and key roles of vascular cells.

Enhancing drug repurposing on graphs by integrating drug molecular structure as feature

This paper improves drug repurposing by integrating 2D drug molecular structures into graph neural networks, achieving higher AUROC and AUPRC scores than previous methods.

Orphan Drugs and Rare Diseases: Unveiling Biological Patterns through Drug Repurposing

This paper examines the evolution of orphan drug development and identifies biological patterns in rare diseases treated with repurposed drugs.