X-Admix: An Interpretable Multimodal Cross-Attention Framework for Integrating Genotype, Local Ancestry, and Social Drivers of Health in Admixed African American Populations
Nahian Tahmin, Lokesh K. Chinthala, Tesfaye Mersha Baye…·Anahita Khojandi
Author
Cincinnati Children's Hospital Medical CenterORCID 0000-0002-9189-8447Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
8 papers
Recent·Most cited
Nahian Tahmin, Lokesh K. Chinthala, Tesfaye Mersha Baye…·Anahita Khojandi
Euiseong Ko, Sai Phani Parsa, Sai Kosaraju…·Mingon Kang
This paper introduces FairHICON, a fairness-aware supervised hierarchical contrastive learning method that identifies sex-specific and common genomic drivers, improving predictive performance and reducing sex-based performance gaps in cancer and asthma datasets.
Sai Phani Parsa, Sai Kosaraju, Euiseong Ko…·Mingon Kang
PIMO improves multi-omics integration by modeling pathway-based interactions, enhancing survival analysis and interpretability in cancer datasets.
Leah Claire Kottyan, Scott Richards, Morgan E Tracy…·Kenneth M. Kaufman
The paper presents a genetic resource of 15,684 individuals of African ancestry, demonstrating its utility in replicating and discovering disease associations.
Aaron Shulkin, Perman Pandal, Eliseo T Vazquez…·Javier E. López
The paper identifies 8 new sex-specific transcriptional pathways in acute myocardial infarction using sex-specific differential gene expression analysis, showing significant differences in pathway composition between males and females.
Dale S. Hardy, Jane T. Garvin, Tesfaye Mersha Baye
The paper examines how ancestry-specific polygenic risk scores interact with diet and physical activity to influence ASCVD risk in European Americans and African Americans.
Niall J. Lennon, Leah Claire Kottyan, C. Kachulis…·Eimear E. Kenny
The paper selects and validates ten polygenic risk scores for clinical use in diverse populations, focusing on chronic diseases and addressing disparities in predictive performance.