Multicellular feedback control of a genetic toggle-switch in microbial consortia
Davide Fiore, Davide Salzano, Enric Cristòbal-Cóppulo, Josep M. Olm, Mario di Bernardo
The paper designs a synthetic microbial consortium with three cell populations to control a bistable toggle-switch in target cells through orthogonal quorum sensing feedback.
IEEE Control Systems Letters · Jun 9, 2020Peer-reviewedSynthetic Biology