Luca Galbusera

Transient transcription factor depletions explain diverse single-cell responses of LexA target promoters to mild DNA damage

The paper quantifies single-cell gene expression dynamics of LexA target promoters in E. coli under DNA damage, showing stochastic bursts driven by transient LexA concentration dips.

Using fluorescence flow cytometry data for single-cell gene expression analysis in bacteria

The paper develops a method for quantitative analysis of fluorescence flow cytometry data in bacteria and introduces an open-source tool for this purpose.

Noise propagation shapes condition-dependent gene expression noise in Escherichia coli

The paper quantifies transcriptional noise in E. coli across growth conditions and shows that noise is shaped by regulatory propagation from transcription factors.

A prize-collecting Steiner tree application for signature selection to stratify diffuse large B-cell lymphoma subtypes

The paper applies a prize-collecting Steiner tree method to select a gene signature for classifying diffuse large B-cell lymphoma subtypes, outperforming existing methods.