Antibiotics damage the colonic mucus barrier in a microbiota-independent manner
Jasmin Sawaed, Lilach Zelik, Y. Levin, Rachel H. Feeney, Maria Naama, A. Gordon, Mor Zigdon, Elad Rubin, Shahar Telpaz, Sonia Modilevsky, Shira Ben-Simon, Aya Awad, Sarina Harshuk-Shabso, Meital Nuriel‐Ohayon, Michal Werbner, , Shai Bel
This study shows antibiotics damage the colonic mucus barrier independently of microbiota, leading to bacterial penetration and IBD exacerbation.
Science Advances · Sep 11, 2024Peer-reviewedImmunology