Quantification of disease-associated RNA tandem repeats by nanopore sensing
Gerardo Patiño‐Guillén, Jovan Pešović, Marko Panić, Max K. Earle, Anastasija Ninkovic, Sergiu Petrusca, Dusanka Savic Pavicevic, Ulrich F. Keyser, Filip Bošković
This paper introduces a nanopore-based method to directly quantify RNA tandem repeats, achieving 18-nucleotide resolution and successfully detecting disease-associated repeats in DM1, DM2, and CCHS1.
Nature Communications · May 8, 2026Peer-reviewedBiochemistry