The 3D nuclear position and compartmentalization of genes prime their response to mechano-confinement
Saleh Oshagi, Oda Hovet, Andrea Halaburková, Cinzia Progida, Jonas Paulsen
The paper investigates how 3D nuclear positioning and compartmentalization of genes influence transcriptional responses to mechanical confinement using Hi-C and transcriptome analyses.
bioRxiv · Nov 6, 2025 · PreprintGenomics