In Vitro Modulation of MECP2 Expression via Antisense Inhibition of miR-132-3p in SH-SY5Y Cells
Arda Örçen, Beyza Servet Göncü, Barış Ekici, Burak Tatlı, Emrah Yücesan
This study shows that inhibiting miR132-3p with ASOs increases MECP2 mRNA in SH-SY5Y cells, suggesting a potential therapeutic approach for Rett syndrome.
bioRxiv · Oct 6, 2025 · PreprintGenetics