Equi-depth pooling for standardized and cost-effective Adaptive Immune Receptor Repertoire sequencing (AIRRseq)
Thomas-Wolf Verdonckt, Marek Sahulčík, Caroline Struyfs, Anne-Sofie Vermeersch, Koen Bartholomeeusen, Filip Van Nieuwerburgh, Ole Lagatie, Kevin K. Ariën
This paper introduces equi-depth pooling to balance sequencing depth in bulk AIRRseq, reducing costs and eliminating sampling bias.
bioRxiv · Aug 1, 2026 · PreprintBioinformatics