Tandem Requirement for Full Renal D1R and D5R Activity
Selim Rozyyev, Annabelle P. Crusan, Andrew Chua Tiu, Julie A. Jurgens, Justin Michael Quion, Laureano D. Asico, Robin Allen Felder, Van Anthony M. Villar
This study shows that D1R and D5R receptors in renal proximal tubules cooperate through heterodimerization to regulate cAMP production and sodium transport, with fenoldopam enhancing their interaction.
bioRxiv · Aug 15, 2019 · PreprintMolecular Biology