Leveraging a Billion-Edge Knowledge Graph for Drug Re-purposing and Target Prioritization using Genomically-Informed Subgraphs
Brian J. Martin, Howard J. Jacob, Philip J. Hajduk, Elaine Wolfe, Loren Chen, Henry Crosby, Matthew Lefever, Richard Wendell
The paper uses a large knowledge graph to identify potential drug repurposing candidates by linking drugs to diseases through genetic evidence.
bioRxiv · Dec 20, 2022 · PreprintBioinformatics