Author

Hanon Solomon McShea

University of California, San FranciscoORCID 0000-0002-9341-4899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:multiple species· 1 Research Focus:phylogenetics / evolution· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Paula V. WelanderiD· 2 shared Babatunde O. OlagunjuiD· 1 shared Brett J. BakeriD· 1 shared Bùi Quang MinhiD· 1 shared Cuong Cao DangiD· 1 shared Jennifer JamesiD· 1 shared Joanna MaseliD· 1 shared Jochen J. BrocksiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersEvolutionary Biology

Paula V. WelanderORCID

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Author profile →

3 papers

Recent·Most cited

The evolutionary history and modern diversity of triterpenoid cyclases

Hanon Solomon McShea, Robb A. Viens, Babatunde O. Olagunju, José‐Luis Giner, Paula V. Welander

This study investigates the evolutionary history and functional diversity of triterpenoid cyclases using biochemical assays and evolutionary models, revealing deep divergence and potential positive selection in key enzyme regions.

Molecular Biology and Evolution · Aug 15, 2025Peer-reviewedEvolutionary Biology

Archaeal lineages related to eukaryotes encode functional diterpenoid cyclases

Hanon Solomon McShea, Valerie De Anda, Jochen J. Brocks, Paula V. Welander, Brett J. Baker

The paper identifies and characterizes diterpenoid cyclases in Asgardarchaeota, showing they produce bicyclic halimadienyl pyrophosphate, potentially relevant to microbial persistence.

bioRxiv · Feb 7, 2025 · PreprintMicrobiology

nQMaker: estimating time non-reversible amino acid substitution models

Cuong Cao Dang, Bùi Quang Minh, Hanon Solomon McShea, Joanna Masel, Jennifer James, Vinh Sy Le, Robert Lanfear

nQMaker estimates time non-reversible amino acid substitution models and rooted phylogenetic trees from protein sequence alignments, showing improved model fit across diverse datasets.

Systematic Biology · Feb 2, 2022Peer-reviewedBioinformatics